TB-500 (Thymosin Beta-4) 5mg – Premium Research-Grade Peptide for Tissue Repair & Regeneration Studies
Introduction to TB-500: A Breakthrough Peptide for Scientific Research
Thymosin Beta-4 (TB-500) is a naturally occurring 43-amino-acid peptide that plays a critical role in cell migration, tissue repair, and actin regulation. As a key focus of wound healing, anti-inflammatory, and regenerative medicine research, TB-500 has demonstrated significant potential in preclinical models for studying:
Tissue regeneration mechanisms (tendons, ligaments, muscle)
Angiogenesis (blood vessel formation) pathways
Anti-fibrotic effects in organ damage models
Modulation of inflammatory cytokines
Actin cytoskeleton reorganization
At EvoHelix.shop, we provide ≥99% pure, HPLC-verified TB-500 strictly for controlled laboratory research purposes. This product is not intended for human or veterinary use and should only be handled by qualified researchers in compliance with all institutional guidelines.
Why Choose EvoHelix TB-500 for Your Research?
1. Unmatched Purity & Precision
- ≥99% purity (HPLC-verified) – No impurities or truncated sequences
- Lyophilized powder format – Optimal stability and easy reconstitution
- Batch-specific Certificate of Analysis (COA) – Full transparency
2. Key Research Applications
- Wound healing models (diabetic ulcers, burns, surgical recovery)
- Musculoskeletal injury studies (tendon/ligament repair in murine models)
- Cardiovascular research (myocardial infarction, endothelial cell migration)
- Neurodegenerative studies (potential neuroprotective effects)
3. Scientifically Validated Mechanisms
- Upregulates cell migration via actin binding (Nature, 2021)
- Reduces pro-inflammatory cytokines (IL-1β, TNF-α)
- Stimulates keratinocyte proliferation (Journal of Investigative Dermatology)
4. EvoHelix Quality Guarantee
USP-grade manufacturing facilities
Sterile lyophilization process
Strict ISO 9001 quality control
TB-500 vs. Other Regenerative Peptides
| Peptide | Primary Research Use | Key Advantage | Stability |
|---|---|---|---|
| TB-500 | Tissue repair, angiogenesis | Systemic effects | Stable at -20°C |
| BPC-157 | Localized wound healing | GI tract focus | Room temp (short term) |
| PEG-MGF | Muscle regeneration | IGF-1 pathway | Requires -80°C |
Why TB-500 Stands Out:
→ Broader systemic activity than localized peptides
→ More stable than growth factors like IGF-1
→ Synergistic with BPC-157 in trauma models
Research Protocol Guidelines
1. In Vitro Studies
- Suggested concentration: 1-10 ng/mL in cell culture media
- Ideal for: Fibroblast migration assays, endothelial tube formation
2. Murine Model Administration
- Subcutaneous/IP dosage: 2-5 mg/kg 2x/week
- Oral bioavailability: <5% (not recommended)
3. Reconstitution & Storage
- Solvent: Sterile bacteriostatic water or PBS
- Storage: -20°C for long-term; 4°C for 30 days post-reconstitution
- Avoid: Freeze-thaw cycles, light exposure
Safety & Compliance
For research use only – Not for human/animal consumption
Requires IACUC approval for vertebrate studies
PPE required (gloves, lab coat, eye protection)
Regulatory Status:
- Not FDA-approved for any application
- Complies with 21 CFR §210/211 (cGMP for pharmaceuticals)
Why EvoHelix?
IRB/IACUC documentation support
Bulk quantities for longitudinal studies
Discreet shipping to US research facilities
MSDS & stability data included
Frequently Asked Questions
1. Is TB-500 legal for US research?
-
Yes, for non-human studies under ethical guidelines.
2. How does TB-500 compare to BPC-157?
-
TB-500 has broader systemic effects, while BPC-157 excels in localized repair.
3. What’s the shelf life?
-
24 months at -20°C unopened; 30 days post-reconstitution at 4°C.
Order EvoHelix TB-500 Today
Catalog #: EBX-TB500-5
Form: Lyophilized powder
Purity: ≥99% (HPLC)
Molecular Weight: 4963.5 Da
CAS #: 77591-33-4
Disclaimer: This product is for research purposes only. By purchasing, you confirm it will not be used for human/veterinary applications.
Advance your regenerative research with EvoHelix – where science meets precision!


CAS Number:77591-33-4

