MOTS-C 10 x 10mg Kit – Mitochondrial-Derived Peptide for Metabolic, Anti-Aging & Performance Research
Comprehensive Scientific Overview
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid mitochondrial-derived peptide that has emerged as one of the most exciting breakthroughs in metabolic, anti-aging, and exercise performance research. Encoded within the mitochondrial genome, MOTS-c regulates nuclear gene expression, glucose metabolism, and insulin sensitivity, making it a powerful tool for studying age-related metabolic decline, obesity, and mitochondrial dysfunction.
At EvoHelix, we provide high-purity MOTS-c peptide (≥98%), rigorously tested via HPLC and mass spectrometry to ensure optimal stability and efficacy for laboratory research. This product is intended solely for in vitro and animal model research under controlled conditions and is not for human or veterinary use.
MOTS (Mitochondrial ORF of the 12S rRNA-c) is a 16-amino acid mitochondrial-derived peptide with powerful effects on glucose metabolism, insulin sensitivity, and cellular longevity. Ideal for studying:
Metabolic disorders (diabetes/obesity models)
Anti-aging & lifespan extension
Exercise performance & muscle recovery
Neuroprotection & cognitive function
Order now at EvoHelix.shop for premium research peptides!
Disclaimer: This product is for laboratory research purposes only. Not for human or animal consumption.
Key Research Applications of MOTS-c
1. Metabolic Regulation & Insulin Sensitivity
MOTS has been shown to enhance glucose uptake and improve insulin sensitivity, making it a valuable peptide for studying:
- Type 2 diabetes models
- Obesity-related metabolic dysfunction
- Insulin resistance mechanisms
Mechanism of Action:
- Activates AMPK pathway – Enhances cellular energy sensing and glucose metabolism (Lee et al., 2015).
- Upregulates GLUT4 translocation – Improves glucose uptake in skeletal muscle (Reynolds et al., 2021).
- Modulates mitochondrial biogenesis – Supports efficient ATP production (Kumagai et al., 2020).
2. Anti-Aging & Longevity Research
MOTS has demonstrated potent anti-aging effects by:
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Reducing oxidative stress – Protects against mitochondrial DNA damage (Kim et al., 2018).
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Enhancing cellular stress resistance – Upregulates antioxidant pathways (Zempo et al., 2022).
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Promoting lifespan extension – Observed in C. elegans and murine models (Wan et al., 2020).
3. Exercise Performance & Muscle Endurance
MOTS has been studied for its ergogenic potential, including:
- Enhancing exercise capacity – Improves endurance in animal models (Qin et al., 2018).
- Reducing muscle fatigue – Supports ATP regeneration (Yamamoto et al., 2021).
- Promoting muscle recovery – Accelerates repair post-exercise (Mendelsohn et al., 2022).
4. Neuroprotection & Cognitive Function
Emerging research suggests MOTS may:
- Protect against neurodegeneration – Reduces amyloid-beta toxicity (Cohen et al., 2022).
- Enhance cognitive function – Improves memory retention in aging models (Lu et al., 2023).
- Modulate neuroinflammation – Suppresses microglial activation (Zhang et al., 2021).
Recommended Research Dosages
Note: These are research guidelines only. Not for human or veterinary use.
| Research Model | Suggested Dosage Range | Administration Route |
|---|---|---|
| In vitro studies | 10-100 µM | Cell culture media |
| Animal models (mice) | 0.5-5 mg/kg | IP or subcutaneous |
| Exercise studies | 1-3 mg/kg (pre-exercise) | Subcutaneous |
Why Choose MOTS-c from EvoHelix?
≥98% HPLC-verified purity
Lyophilized powder for long-term stability
Third-party lab testing available
Fast & discreet USA shipping
Research-use only (non-human/non-veterinary)
Storage & Handling
- Store at -20°C for long-term stability
- Reconstitute with sterile bacteriostatic water
- Avoid repeated freeze-thaw cycles
Order MOTS-c for Your Research Today!
MOTS is a cutting-edge research peptide with applications in metabolic disease, anti-aging, exercise science, and neuroprotection. At EvoHelix, we provide the highest quality peptides for scientific investigation only.
Disclaimer: This product is sold exclusively for laboratory research purposes. It is not intended for human consumption, medical treatment, or veterinary use. By purchasing, you confirm compliance with all applicable regulations.
